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This role was delegated to ABADS by the International Society for Horticultural Science in 2002.Datura species are usually planted annually from the seed produced in the spiny pods, but with care, plants can be overwintered.All species of Datura are poisonous, especially their seeds and flowers.Some South American plants formerly thought of as Datura are now treated as belonging to the distinct genus Brugmansia (Brugmansia differs from Datura in that it is woody, making shrubs or small trees, and it has pendulous flowers, rather than erect ones).

From 1950 to 1965, the State Chemical Laboratories in Agra, India, investigated 2,778 deaths caused by ingesting Datura.

Many tragic incidents result from modern users ingesting Datura.

For example, in the 1990s and 2000s, the United States media contained stories of adolescents and young adults dying or becoming seriously ill from intentionally ingesting Datura.

The leaves are alternate, 10–20 cm long and 5–18 cm broad, with a lobed or toothed margin.

The flowers are erect or spreading (not pendulous like those of Brugmansia), trumpet-shaped, 5–20 cm long and 4–12 cm broad at the mouth; colors vary from white to yellow, pink, and pale purple.

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Because of the presence of these substances, Datura has been used for centuries in some cultures as a poison.